|
Symbol Name ID |
Nppa
natriuretic peptide type A MGI:97367 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Left atrial enlargement |
Left ventricular hypertrophy |
Right ventricular dilatation |
Dilatation of the ventricular cavity |
Cardiomyopathy |
Atrial cardiomyopathy |
Premature coronary artery atherosclerosis |
Vascular dilatation |
Stroke |
Reduced left ventricular ejection fraction |
Elevated left ventricular end-diastolic diameter |
Aortic valve stenosis |
Tricuspid regurgitation |
Hypertension |
Absent P wave |
Prolonged P wave |
Prolonged PR interval |
Prolonged QRS complex |
Prolonged QTc interval |
ST segment elevation |
Sinus bradycardia |
Bradycardia |
Sudden cardiac death |
Palpitations |
Atrial arrhythmia |
Atrial fibrillation |
Paroxysmal atrial fibrillation |
Permanent atrial fibrillation |
Atrial flutter |
Atrial standstill |
Premature atrial contractions |
Supraventricular tachycardia |
Myocardial infarction |
Syncope |
| Disease(s) Associated with NPPA | ||||||||||||||||||||||||||||||||||
| atrial standstill 2 | ||||||||||||||||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||||||||||||||||
| familial atrial fibrillation |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal vascular smooth muscle morphology |
heart left ventricle hypertrophy |
heart right ventricle hypertrophy |
increased heart weight |
enlarged heart |
abnormal cardiovascular system physiology |
decreased cardiac output |
abnormal vascular resistance |
abnormal heart right ventricle pressure |
increased right ventricle peak pressure |
increased heart rate |
pulmonary hypertension |
abnormal systemic arterial blood pressure |
hypertension |
salt-sensitive hypertension |
increased systemic arterial diastolic blood pressure |
|
| Availability | Mouse Genotype | |||||||||||||||||
| Nppatm1Unc/Nppatm1Unc | * | |||||||||||||||||
| Nppatm1Unc/Nppa+ | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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